Preheat the air fryer to 400 degrees F.
Combine ground beef, salt, pepper, egg, and breadcrumbs in a mixing bowl. Thoroughly mix.
Cut cheese into ½” cubes.
Use a medium cookie scoop to form equal sized burger bites. Roll the ground beef mixture between your palms and form into a ball. Make a small divot in the center, then place the cheese cube inside. Form the ground beef around the cheese.
Wrap each burger bite with bacon. Tuck the ends of the bacon in as you wrap, or secure with a toothpick.
Place burger bites in a single layer in the air fryer and cook for 12 minutes. Stop halfway through to flip and evenly crisp the bacon.
Sprinkle burgers with sesame seeds and serve with ketchup and mustard to dip.