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Preheat the air fryer to 400 degrees F.
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Combine ground beef, salt, pepper, egg, and breadcrumbs in a mixing bowl. Thoroughly mix.
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Cut cheese into ½” cubes.
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Use a medium cookie scoop to form equal sized burger bites. Roll the ground beef mixture between your palms and form into a ball. Make a small divot in the center, then place the cheese cube inside. Form the ground beef around the cheese.
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Wrap each burger bite with bacon. Tuck the ends of the bacon in as you wrap, or secure with a toothpick.
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Place burger bites in a single layer in the air fryer and cook for 12 minutes. Stop halfway through to flip and evenly crisp the bacon.
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Sprinkle burgers with sesame seeds and serve with ketchup and mustard to dip.